Effect of Particle Size of Ophiopogon japonicus and Dioscorea opposita Meal Replacement Powder on Its in Vitro Hypoglycemic and Hypolipidemic Activities
Article Sidebar
Hypoglycemic Activity,
Hypolipidemic Activity,
Ophiopogon japonicus,
Dioscorea opposita
Main Article Content
Xue Wu
Jieya Hu
Ling Yang
Zhanglei Zhang
Xianlu Lei
Abstract
Background: Ophiopogon japonicus and Dioscorea opposita are prominent medicinal and edible raw materials for functional foods. In meal replacement powders, particle size is a critical factor influencing biological activities.
Aim: This study investigated the effect of particle size on the in vitro hypoglycemic and hypolipidemic functions of an O. japonicus and D. opposita meal replacement powder.
Methods: Botanical powders were prepared at 40, 60, 80, 100, and 120 mesh. Various in vitro functional indicators related to blood glucose and lipid reduction—such as glucose dialysis delay index, glucose adsorption, α-amylase inhibition, and cholesterol/sodium cholate binding capacities—were evaluated.
Result: As the crushing degree increased, all indicators initially increased and subsequently decreased. The glucose dialysis delay index and glucose adsorption capacity peaked at 100 mesh. The strongest α-amylase inhibition occurred at 80 mesh, reaching 75.48%. Additionally, cholesterol adsorption capacity, sodium cholate adsorption capacity, and sodium cholate binding capacity reached their maximum levels at 100 mesh, yielding 1.38 mg/g, 16.01 mg/g, and 69.41%, respectively.
Conclusion: Meal replacement powders processed through an 80-mesh or 100-mesh sieve possess optimal hypoglycemic and hypolipidemic potential. This study provides theoretical support for the formulation optimization of O. japonicus-D. opposita powders and serves as a processing reference for the industrial production of homologous functional foods.
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Copyright (c) 2026 Xue Wu, Jieya Hu, Ling Yang, Zhanglei Zhang, Xianlu Lei
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